Inheritance - MPS II

Hunter Syndrome has a different form of inheritance from all the other MPS disorders as it is "sex linked", like haemophilia. Girls may be carriers of the disorder but, except in rare cases, only boys will be affected.

All families of children with Hunter Syndrome should seek further information from their doctor or genetic counsellor before planning to have more children. If the mother is a carrier there is a 50% risk that any boy born will have the disorder.

The sisters and maternal aunts of a person with Hunter Syndrome may be carriers of the disorder who would also have a 50% chance of passing the syndrome to a son. There are tests available for carriers, so it is important for all female relatives on the mother's side to seek advice from their doctor.

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